![Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews](https://journals.physiology.org/cms/10.1152/physrev.00001.2019/asset/images/medium/z9j0012029260007.gif)
Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews
![Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews](https://journals.physiology.org/cms/10.1152/physrev.00001.2019/asset/images/medium/z9j0012029260006.gif)
Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews
![JCI Insight - Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function JCI Insight - Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function](https://df6sxcketz7bb.cloudfront.net/manuscripts/121000/121264/medium/jci.insight.121264.f4.jpg)
JCI Insight - Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function
![Antioxidants | Free Full-Text | Methylglyoxal-Induced Dysfunction in Brain Endothelial Cells via the Suppression of Akt/HIF-1α Pathway and Activation of Mitophagy Associated with Increased Reactive Oxygen Species Antioxidants | Free Full-Text | Methylglyoxal-Induced Dysfunction in Brain Endothelial Cells via the Suppression of Akt/HIF-1α Pathway and Activation of Mitophagy Associated with Increased Reactive Oxygen Species](https://pub.mdpi-res.com/antioxidants/antioxidants-09-00820/article_deploy/html/images/antioxidants-09-00820-ag.png?1599119370)
Antioxidants | Free Full-Text | Methylglyoxal-Induced Dysfunction in Brain Endothelial Cells via the Suppression of Akt/HIF-1α Pathway and Activation of Mitophagy Associated with Increased Reactive Oxygen Species
Methylglyoxal attenuates insulin signaling and downregulates the enzymes involved in cholesterol biosynthesis - Molecular BioSystems (RSC Publishing)
![Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies | Bentham Science Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies | Bentham Science](http://www.eurekaselect.com/images/graphical-abstract/cdm/17/4/8.gif)
Methylglyoxal, A Metabolite Increased in Diabetes is Associated with Insulin Resistance, Vascular Dysfunction and Neuropathies | Bentham Science
Methylglyoxal Forms Diverse Mercaptomethylimidazole Crosslinks with Thiol and Guanidine Pairs in Endogenous Metabolites and Proteins | ACS Chemical Biology
![Hyperglycaemia-induced methylglyoxal accumulation potentiates VEGF resistance of diabetic monocytes through the aberrant activation of tyrosine phosphatase SHP-2/SRC kinase signalling axis | Scientific Reports Hyperglycaemia-induced methylglyoxal accumulation potentiates VEGF resistance of diabetic monocytes through the aberrant activation of tyrosine phosphatase SHP-2/SRC kinase signalling axis | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-018-33014-9/MediaObjects/41598_2018_33014_Fig1_HTML.png)
Hyperglycaemia-induced methylglyoxal accumulation potentiates VEGF resistance of diabetic monocytes through the aberrant activation of tyrosine phosphatase SHP-2/SRC kinase signalling axis | Scientific Reports
![Methylglyoxal – An emerging biomarker for diabetes mellitus diagnosis and its detection methods - ScienceDirect Methylglyoxal – An emerging biomarker for diabetes mellitus diagnosis and its detection methods - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0956566319301915-gr1.jpg)
Methylglyoxal – An emerging biomarker for diabetes mellitus diagnosis and its detection methods - ScienceDirect
![Nutrients | Free Full-Text | Dietary Fructose Feeding Increases Adipose Methylglyoxal Accumulation in Rats in Association with Low Expression and Activity of Glyoxalase-2 Nutrients | Free Full-Text | Dietary Fructose Feeding Increases Adipose Methylglyoxal Accumulation in Rats in Association with Low Expression and Activity of Glyoxalase-2](https://www.mdpi.com/nutrients/nutrients-05-03311/article_deploy/html/images/nutrients-05-03311-g001.png)
Nutrients | Free Full-Text | Dietary Fructose Feeding Increases Adipose Methylglyoxal Accumulation in Rats in Association with Low Expression and Activity of Glyoxalase-2
![Plasma methylglyoxal and glyoxal are elevated and related to early membrane alteration in young, complication-free patients with Type 1 diabetes | SpringerLink Plasma methylglyoxal and glyoxal are elevated and related to early membrane alteration in young, complication-free patients with Type 1 diabetes | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs11010-007-9535-1/MediaObjects/11010_2007_9535_Fig1_HTML.gif)
Plasma methylglyoxal and glyoxal are elevated and related to early membrane alteration in young, complication-free patients with Type 1 diabetes | SpringerLink
![Advanced glycation endproducts in diabetes-related macrovascular complications: focus on methylglyoxal: Trends in Endocrinology & Metabolism Advanced glycation endproducts in diabetes-related macrovascular complications: focus on methylglyoxal: Trends in Endocrinology & Metabolism](https://www.cell.com/cms/attachment/27ca6d10-96e5-49ac-abcb-8c88e75ac5f3/gr1_lrg.jpg)
Advanced glycation endproducts in diabetes-related macrovascular complications: focus on methylglyoxal: Trends in Endocrinology & Metabolism
![Methylglyoxal, AGE formation and the glyoxalase system. (A) Glycolytic... | Download Scientific Diagram Methylglyoxal, AGE formation and the glyoxalase system. (A) Glycolytic... | Download Scientific Diagram](https://www.researchgate.net/publication/311160269/figure/fig1/AS:434099073622019@1480508692770/Methylglyoxal-AGE-formation-and-the-glyoxalase-system-A-Glycolytic-pathways-leading.png)
Methylglyoxal, AGE formation and the glyoxalase system. (A) Glycolytic... | Download Scientific Diagram
![Figure 3 | Biochemical Studies on Methylglyoxal-Mediated Glycated Histones: Implications for Presence of Serum Antibodies against the Glycated Histones in Patients with Type 1 Diabetes Mellitus Figure 3 | Biochemical Studies on Methylglyoxal-Mediated Glycated Histones: Implications for Presence of Serum Antibodies against the Glycated Histones in Patients with Type 1 Diabetes Mellitus](https://static-02.hindawi.com/articles/isrn/volume-2013/198065/figures/198065.fig.003.jpg)
Figure 3 | Biochemical Studies on Methylglyoxal-Mediated Glycated Histones: Implications for Presence of Serum Antibodies against the Glycated Histones in Patients with Type 1 Diabetes Mellitus
![Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews](https://journals.physiology.org/cms/10.1152/physrev.00001.2019/asset/images/medium/z9j0012029260001.gif)
Methylglyoxal, a Highly Reactive Dicarbonyl Compound, in Diabetes, Its Vascular Complications, and Other Age-Related Diseases | Physiological Reviews
Bestimmung von Glyoxal u Lebensmitteln und im Serum Eine Basis für die Abschätz Exposition und Bio stimmung von Glyoxal und Me
![Routes for the in vivo production of glyceraldehyde (GA)/methylglyoxal... | Download Scientific Diagram Routes for the in vivo production of glyceraldehyde (GA)/methylglyoxal... | Download Scientific Diagram](https://www.researchgate.net/publication/349887703/figure/fig2/AS:999096152240128@1615214493332/Routes-for-the-in-vivo-production-of-glyceraldehyde-GA-methylglyoxal-MGO-The.png)
Routes for the in vivo production of glyceraldehyde (GA)/methylglyoxal... | Download Scientific Diagram
![Methylglyoxal effects on diabetes induction or diabetic complications. | Download Scientific Diagram Methylglyoxal effects on diabetes induction or diabetic complications. | Download Scientific Diagram](https://www.researchgate.net/profile/Yousef-Shamsaldeen-2/publication/297409919/figure/tbl1/AS:1127122097717249@1645738257542/Methylglyoxal-effects-on-diabetes-induction-or-diabetic-complications_Q640.jpg)